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KMID : 0371019960290030639
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Journal of Preventive Medicine and Public Health
1996 Volume.29 No. 3 p.639 ~ p.656
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The Case-Control Study on the Risk Factors of Cerebrovascular Diseases and Coronary Heart Diseases
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Park Jong-Ku
Kim Hun-Joo
Park Kum-Soo
Lee Seong-Soo
Chang Sei-Jin
Shin Kye-Chul
Kwon Sang-Ok
Koh Sang-Baek
Lee Eun-Kyoung
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Abstract
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Cerebrovascular disease and coronary heart disease are the first and the fourth common causes of death among adults in Korea. Reported risk factors of these diseases are mostly alike. But. some risk factors of one of these diseases may prevent other diseases. Therefore, we tried to compare and discriminate the risk factors of these diseases.
We recruited four case groups and four control groups among the: patients who were admitted to Wonju Christian Hospital from March, 1994 to November,´, 1995. Four control groups were matched with each of four case groups by age and sex. The Number of patients in each of four case and control groups were 106 and 168 for acute myocardial infarction(AMI), 84 and 133 for subarachnoid hemorrhage(SAH), 102 and 148 for intracerebral hemorrhage(ICH), and 91 and 182 for ischemic stroke(IS) respectively.
Factors whose levels were significantly higher in AMI and IS than in responding control group (RCG) were education, economic status, and triglyceride. Factors whose levels were significantly lower in hemorrhagic stroke than in RCG were age of menarch, and prothrombin time. The factor whose level was higher in AMI than in RCG was uric acid. The fact, or whose level was higher in AMI, ICH, and SAH than in RCG was blood sugar. Factors whose levels were significantly higher in all the case groups than in RCG were earlobe crease, Quetelet index, white blood cell count, hemoglobin, hematocrit, and total cholesterol.The list of risk factors were somewhat different among the four diseases , though none of the risk factor to the one disease except prothrombin time acted as a preventive factor to the other diseases.
The percent of grouped cases correctly classified was higher in the discrimination of ischemic diseases(AMI and IS) from hemorrhagic diseases(SAH and ICH) than in the discrimination of cerebrovascular disease from AML The factors concerned in the discrimination of ischemic diseases from hemorrhagic diseases were prothrombin time, earlobe crease, gender, age, uric acid, education, albumin, hemoglobin, the history of taking steroid, total cholesterol, and hematocrit according to the selection order through forward selection.
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KEYWORD
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Risk Factors, Cerebrovascular Disease, Coronary Heart Disease
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